NR1H4 and metabolic dysfunction-associated steatotic liver disease: But the nuclear receptor of bile acids, farnesoid X receptor (FXR), and its mediated short heterodimer partner (SHP) were not significantly different between the two groups, which indicates that the reason why bile acids can relieve NAFLD may be the alteration of gut bacteria and endotoxin [17] besides through FXR-sterol response element-binding protein-1c (SREBP-1c) cascade signal transduction system to regulate hepatic triglyceride metabolism [18, 19].