In a prospective cohort study of 230 patients undergoing chronic peritoneal dialysis, Wang et al. reported that NT-pro-BNP was an independent risk marker of congestive heart failure, death, or a combined end-point including death and other adverse cardiovascular outcomes [22] (odds ratios varied between 4.25 and 9.1 for the fourth compared to the 1st quartile of NT-pro-BNP). This evidence concerns the gene NPPB and congestive heart failure.