Significant differences in OS (Fig. 3A) and DFS (Fig. 3B) were observed in a study including ADC patients; the median survival time was significantly shorter for cases with increased IGF-1R mRNA expression than for those without changes (OS median survival 26.51 vs. 47.77 months, P = 0.017; DFS median survival 17.44 vs. 37.65 months, P = 0.045). The gene discussed is IGF1R; the disease is AIDS dementia complex.