AKT1 and lung carcinoma: Although phosphorylation status of filamin A on patient prognostic outcomes was not evaluated due to the unavailability of such data, a proportional increase of the phosphorylated filamin A can be envisioned among those patients with a higher level of overall expression of filamin A. Accordingly, the prediction of poorer survival of the never-smoked lung cancer patients with adenocarcinoma is in great agreement with our experimental findings showing As3+ induces Akt-dependent phosphorylation of filamin A and cell migration.