The results indicate that plasma and urine NGAL (AUROC 0.823, 95% CI 0.730 to 0.916 and AUROC 0.855, 95% CI 0.777 to 0.933, respectively) performed well for the diagnosis of AKI occurrence and that plasma and urine Cys-C (AUROC 0.795, 95% CI 0.704 to 0.885 and AUROC 0.772, 95% CI 0.682 to 0.862, respectively) and sTREM-1 (AUROC 0.794, 95% CI 0.708 to 0.880 and AUROC 0.707, 95% CI 0.610 to 0.805, respectively) performed fairly well. This evidence concerns the gene LCN2 and acute kidney injury.