To assess the predictive values of plasma and urine NGAL, Cys-C, and sTREM-1 for AKI occurrence 24 hours before its diagnosis in patients with sepsis, we used the data of 57 non-AKI sepsis cases on admission and 34 AKI sepsis patients at the last time point before AKI occurrence. The gene discussed is LCN2; the disease is acute kidney injury.