S100A8 and cancer: Among the 28 dysplasias found in DSS-treated cagA-Tg mice, 24 were low-grade dysplasias (LGDs) (polypoid : flat = 7 : 17) and 4 were high-grade dysplasias (HGDs = carcinomas in situ) (polypoid : flat = 3 : 1).