While caspases‐1 and ‐4 are basally expressed in monocyte (THP‐1) and epithelial carcinoma (HT‐29) cell lines, human caspase‐5 and murine caspase‐11 expression is induced in both cell types following stimulation with bacterial lipopolysaccharide or the pleiotrophic cytokine, interferon (IFN)‐γ 32, 34. The gene discussed is IFNG; the disease is carcinoma.