LEF1 and acute lymphoblastic leukemia: We also analyzed the event-free survival (EFS) in the patients and found that there was a significantly shorter EFS in B-ALL patients with LEF1 high expression compared to low expression (4.5 months vs 10.0 months; P = 0.023) (Fig 2B), but no significant difference in EFS was observed in the two groups in T-ALL patients (Fig 2D).