Variations of Fn concentration can be used as indicators of several diseases, such as bladder cancer, liver damage, defibrination syndrome, arterial thrombosis, preterm birth, or ocular damage (Choate and Mosher, 1983; Cembrowski and Mosher, 1984; Weller et al., 1988; Honest et al., 2002; Mosher, 2006; Eissa et al., 2010). Here, FN1 is linked to urinary bladder cancer.