Segregation of these patients into DACH1-high and low expression groups did not reveal significant relationship with clinicopathological parameters of sex, age, liver cirrhosis, tumor size, location, pathological type or the expressions of AFP, but noticeably associated with tumor grading (p = 0.033), TNM staging (p = 0.037) and Ki-67 profiles (p = 0.037) (Table 2). This evidence concerns the gene DACH1 and cirrhosis of liver.