MYO6 and deafness: In hair cells of the cochlea, myosin VI displays dual functions: (1) targeting of protein cargoes to stereocilia, the disturbance of which leads to deafness [6], (2) targeting of cargoes that couple exocytosis and endocytosis, the disturbance of which leads to cell surface shrinkage and disturbed replenishment of vesicles [7, 8].