P-Selectin is, therefore, an important effector in the early inflammatory process and was first successfully used with ultrasound molecular imaging in the detection of renal tissue injury [73] and later in models of myocardial ischemia with the use of sialyl Lewis(x) as a ligand for P-Selectin [85] or anti-P-Selectin antibodies [86]. Here, SELP is linked to myocardial ischemia.