However, our finding that inflammation is similar in Dppi+/+ and Dppi-/- mice 2, 7 and 14 days after infection suggests that Dppi-activated proteases, including neutrophil cathepsin G, do not destroy mycoplasma antigens or immunomodulatory factors to an extent that lessens pneumonia severity during early responses to infection. The gene discussed is CTSG; the disease is infection.