CASP3 and hepatocellular carcinoma: Consistent with the apoptosis staining results, western blotting revealed a significant upregulation of active caspase-3 and cleaved PARP in HCC-LM3 cells treated with 40 μM of resveratrol, whereas a concentration of 80 μM was required to achieve the same effect in Bel-7402 and Huh-7 cells (Fig. S1).