PKM and hepatocellular carcinoma: To examine the mechanism underlying the effect of resveratrol on promoting cell death by inhibiting glycolysis in aerobic glycolytic HCC cells, we measured the effects of resveratrol on the expression of several key glycolytic enzymes, including GLUT1, HK2, PKM2, PFK1/2, and LDH-A in HCC-LM3 and Bel-7402 cells by qRT-PCR.