PKM and hepatocellular carcinoma: Analysis of the potential effect of resveratrol on other glycolytic proteins showed that at a dose of 40 μM, resveratrol downregulated the protein expression of PKM2 in HCC-LM3 and Bel-7402 cells (Fig. 3C-3E), suggesting that resveratrol may inhibit glycolysis at a broad level in aerobic glycolytic HCC cells.