At present, researchers suggest that the cytokine cascade from the innate immune system (mainly monocytes, macrophages and neutrophils) and the activated adaptive immune system (including CD4+, CD8+ T and CD19+ B lymphocytes) are central to the developments of SIRS, compensatory anti-inflammatory response syndrome and OF in AP [1, 7–9]. This evidence concerns the gene CD4 and alkaline phosphatase measurement.