INS and diabetes mellitus: The variables that were significantly different between the 1st quartile and 4th quartile of the ISS formula data comprise age, duration of diabetes, BMI, total insulin dose per lean mass, total fat percentage, arm fat, leg fat, thoracoabdominal fat (absolute and percentage), scapular skinfold, triceps skinfold, total lean mass (absolute and percentage), percentage of total fat, and hip and waist/height ratio.