FOXM1 and colorectal neoplasm: Consistent with the level of FoxM1 protein expression determined using immunostaining analyses, primary colorectal tumors and metastatic lymph nodes had significantly higher levels of FoxM1 mRNA expression than did surrounding normal colorectal tissue from 4 patients by QRT-PCR analysis, the difference between them was statistically significant (Figure 1E p < 0.01).