CSPG4 and cancer: NG2/CSPG4 has been proposed to impact on tumourigenesis and evidence has been accrued suggesting that NG2/CSPG4 alone is able to confer metastatic potential to cancer cells by serving as a multivalent mediator of the cancer cell-host microenvironment interactions and by enhancing drug resistance and protecting cells from stress-induced programmed cell death [49,50].