Clinical correlation of SDC1 expression with disease status specifically refers to its modulation in epithelial neoplastic cells [41-47] and tumour stroma [48], while the PG has been proposed to influence migration and invasion of oral squamous cell carcinoma cells in vitro by interacting with the β1 integrin subunit and the laminin β1 chain [48]. The gene discussed is SDC1; the disease is neoplasm.