MTA2 and neoplasm: At fourth week, tumor volume and weight were significantly larger in BGC-823/MTA2 group than those in NC group (volume: 2885.7 ± 1109.8 mm3 vs. 1509.6 ± 133.2 mm3, P = 0.021; weight: 1.51 ± 0.58 g vs. 0.86 ± 0.17, P = 0.038, Figure 3A).