STAT3 and esophageal cancer: In this paper, we found another way mediated the overexpression of STAT3. The prediction program identified the putative binding site of miR-124 in the 3’UTR of STAT3, and we found that overexpression of miR-124 significantly suppressed the expression of STAT3 and its downstream genes in esophageal cancer cells in vitro and engrafted tumors in vivo.