In 1,022 SCD patients, we scanned the HBS1L-MYB intergenic region (chr6:135,318,635-135,518,635, Figure 1 for genetic association with HbF levels (ln[%HbF]), evaluating 538 SNP (single nucleotide polymorphism) markers from a combination of genome-wide chip array and targeted genotyping. This evidence concerns the gene HBS1L and Schnyder corneal dystrophy.