TGFB1 and urinary bladder cancer: Because EMT is of particular significance as a marker of tumor invasion and metastasis and TGFβ1 treatment represents a classical induction approach for in vitro EMT research, we believe that elaborating both the specific roles of miR-221 in TGFβ1-induced EMT models of bladder cancer and the latent molecular mechanisms will enlarge our theoretical understanding of human bladder cancer and provide future clinical approaches to treating this disease.