ASS1 and cancer: We determined the expression of Ass1 in the3IB2 mouse gastric cancer cell line, and found that its suppression resulted indecreases in cell migration and tumor metastasis in vitro and in vivo.We have previously performed immune-histochemical analysis on gastric cancertissues, and found that ASS1 protein was expressed and localized primarily to thecytoplasm of cancer cells and normal epithelium19.