It is noteworthy that, although focal cortical ischemia is able to stimulate the proliferation and possible neurogenesis of SVZ NSCs identified by YFP immunostaining as well as DCX positive neuroblasts at the SVZ niche, the migration of these neuroblasts towards the cortical ischemic region is minimal compared to the abundant DCX positive cells migrating into the corpus callosum (CC) and striatal areas in proximal MCAo-induced striatal stroke (Fig 1H–1L). This evidence concerns the gene DCX and ischemia.