This finding is consistent with a recent meta-analysis by Wang et al. [14], who found an association between the CYP2C19 PM genotype and increased risk of esophageal cancer (PM vs EM: OR = 2.93, 95% CI: 2.06–4.17) among 308 cases and 644 controls. Here, CYP2C19 is linked to esophageal cancer.