The pooled results based on all included studies showed a significant association between the XRCC1-Arg399Gln polymorphism and prostate cancer risk under the homozygote model GG vs. AA (OR = 1.24, 95%CI = 1.00–1.53, P = 0.048)(Figure 2. The gene discussed is XRCC1; the disease is prostate carcinoma.