TERRA expression is induced in ALT cells (Ng et al., 2009; Arora et al., 2014) and recent evidence indicate that while TERRA levels decrease from S phase to G2 phase in telomerase-positive cancer cells (Porro et al., 2010), TERRA foci significantly increase during S phase and G2 in ALT cells (Flynn et al., 2015). Here, GPT is linked to cancer.