GPR55 and obesity due to melanocortin 4 receptor deficiency: Based upon this expression pattern, there are at least three therapeutic areas in which GPR55 may prove useful: (1) the regulation of energy intake and expenditure, which impacts the fields of obesity and diabetes (Simcocks et al., 2014; Liu et al., 2015); (2) resorption of bone, which impacts the field of osteoporosis (Whyte et al., 2009); and (3) agonist pro-carcinogensis, which impacts many types of cancers (Ford et al., 2010; Andradas et al., 2011; Pineiro et al., 2011; Leyva-Illades and Demorrow, 2013).