TNF and lung carcinoma: The MAK Commission [11] did not discuss that workers exposed to high dust levels (coalminers) showed no evidence of dust overload, demonstrated no lung cancer excess risks and that BAL findings in humans did not replicate the PMN elevations seen in rats, even though signs of dust effects in the BALF (change of surfactant lipids, and SP-A, TNF alpha increase) as well as pneumoconiotic pathology were registered.