Aberrant methylation at the genes B3GATL4 (6p21.3), TNXB (6p21.3), TRIM31 (6p21.3), LY6G5C (6p21.33), KIAA1949/PPP1R18 (6p21.3), and GNL1 (6p21.3) identified in NPC was also hypermethylated in EBV-positive gastric cancers compared to EBV-negative gastric cancers (FDR < 1.6 × 10−90). The gene discussed is LY6G5C; the disease is nasopharyngeal carcinoma.