AFP and hepatocellular carcinoma: Western blot results (Figure 3B, C) also showed that significant decrease of DNA polymerases α, δ and ε at protein level in AFP-expressing HCC cells, with decrease rates 42.91% (p < 0.05, n = 3), 75.91% (p < 0.05, n = 3) and 61.03% (p < 0.05, n = 3) respectively in HepG2, 54.32% (p < 0.05, n = 3), 20.58% (p < 0.05, n = 3) and 53.96% (p > 0.05, n = 2) respectively in Hep3B, but the rates were only 22.88% (p > 0.05, n = 3), 14.53% (p > 0.05, n = 3) and 6.68% (p > 0.05, n = 3) respectively in HL7702, which were consistent with the inhibitions at mRNA level.