ITGAM and glaucoma: In the 3 microbead glaucoma groups (saline, hNP and hNPTD) expression of CD11b and MFG-E8 microglial cell activation (which participate in RGC phagocytosis and apoptosis) were also upregulated (Fig 7F and 7G) and higher than their corresponding levels in the microbead glaucoma group receiving hNPIGF-TD (P < 0.05).