ACE and acute kidney injury: In the lone case where acute kidney injury contributed to the discontinuation of telaprevir, a male patient’s serum creatinine rose from a baseline of 1.5mg/dL to 2.69mg/dL (eGFR 50 to 25mL/min/1.73m2) three weeks after starting telaprevir in the context of severe fatigue and decreased oral intake with ongoing diuretic and angiotensin converting enzyme inhibitor use.