IGF2BP2 and rhabdomyosarcoma: Knockdown of HGMA2 in embryonic rhabdomyosarcoma cells resulted in severe downregulation of IGF2BP2 and knockdown of either HGMA2 or IGF2BP2 led to reduced protein levels encoded by the neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) [49].