And finally, we finished with Breast Cancer 1 (BrCa1), a good example of a protein with an important role in the lipogenic and lipolysis pathways involved in the relationship between obesity and its associated metabolic pathologies BrCa1 is a protein involved in multiple cellular functions, including DNA repair, cell cycle checkpoint control, and transcription associated with the DNA damage as it has been reported in breast and ovarian cancers [58], and ubiquitination, activity developed thanks to the heterodimer with BARD1 [59], among others. Here, BRCA1 is linked to obesity due to melanocortin 4 receptor deficiency.