TNF and hydrops fetalis: Figure 4 shows significantly increased serum TNF-α, IL-6, and leptin associated with 55.6% reduction of adiponectin in HF-control mice as compared with the chow group (P < 0.05), whereas antiresistin oligo treatment markedly decreased the elevation of TNF-α and IL-6 (Figures 4(a) and 4(b), both P < 0.05).