Additionally, we found that CXCL12 and CXCR7—a CXCRL12 receptor—were upregulated during the progression of gastric MALT lymphomas to gastric eDLBCL [112], suggesting at least in part an implication of this signaling pathway in high-grade transformation of gastric MALT lymphomas. The gene discussed is ACKR3; the disease is MALT lymphoma.