MALT lymphoma cells share the same cytological and immunophenotypical (CD20+, CD21+, CD35+, IgM+, and IgD−) features as marginal zone B cells prompting the World Health Organization to designate this lymphoma as “extranodal marginal zone B cell lymphoma of mucosa associated lymphoid tissue (MALT lymphoma)” [8]. This evidence concerns the gene CD40LG and MALT lymphoma.