PTAFR and melanoma: In a dual tumor model, where two melanoma tumors were implanted into syngeneic mice and only one tumor was treated intratumorally with chemotherapeutic agents (melphalan or ETOP) either in syngeneic mice expressing or deficient in the PAF-R, we demonstrated that chemotherapy-generated PAF-R agonists augmented the growth of secondary tumors in a PAF-R dependent manner [29].