Increased values of PTX3 were related to several factors: age; AHF and left ventricular overload expressed by several parameters (increased LVEDP, Killip heart failure class, and increased BNP level); extent of infarct size (as expressed by level of troponin I); renal function (in particular its worsening according to the number of patients with acute kidney injury); and impaired flow of infarct-related arteries (as expressed by TIMI flow before and after PCI). Here, NPPB is linked to acute kidney injury.