Systematic reviews and meta-analyses of these original reports conclude poor prognostic effects of MMP2 and MMP9 in stomach [7,8], breast [9,10], lung [11,12], colorectal [13,14] and ovarian [15] cancers; additionally they showed clinical significance of MMPs in bladder cancer [16] as well as prognostic effect of MMP7 in colorectal cancer [14]. This evidence concerns the gene MMP7 and cancer.