The up-regulated expression of ST6Gal I was first described in colon cancer, but successively confirmed in other carcinomas of breast, liver, cervix, choriocarcinomas, acute myeloid leukemias and some malignancies of the brain as well [18,31,32,33,34,35,36,37,38,39,40]. This evidence concerns the gene ST6GAL1 and breast carcinoma.