The pro-migratory and anti-apoptotic roles have been challenged by several reports that: (1) forced expression of ST6Gal I suppressed the cell migration and enhanced the cell death induced by chemotherapeutic agents in glioma cells [67,100]; (2) ST6Gal I loss was associated with increasing invasiveness in bladder carcinogenesis [101]. Here, ST6GAL1 is linked to glioma.