Additionally, BMP7v inhibited tumor-driven cord formation across a range of human tumor cell models demonstrating that BMP7v is effective in a complex “physiological system.” Our previous results indicated that BMP7v did not alter expression of secreted proangiogenic factors from tumor cells [16], and BMP7v did not alter VEGF or bFGF secretion from the co-culture (data not shown). Here, FGF2 is linked to neoplasm.