For example, the overexpression of the anti-apoptotic bcl-2 family members (Bcl-2, Bcl-xL, MCL1, Bcl-W, A1, and Bcl-B), the suppression of activation of pro-apoptotic members (Bax, BaK, and Bok), the aberrant expression of inhibitors of apoptosis (IAP) proteins and cellular FLICE-like inhibitory protein (C-FLIP) have been found to be related to cancer cells resistance to apoptotic stimuli and have been associated to the progression of several types of tumors [95]. Here, CFLAR is linked to cancer.