The densities of CgA cells in the total colon of IBS patients were 38.6 ± 3.7 and 64.7 ± 4.2 cells/mm2 before and after receiving dietary guidance, respectively; this increase was statistically significant (P = 0.0004) (Figures 1(a) and 2). The gene discussed is CGA; the disease is irritable bowel syndrome.