Moreover, inhibition of visfatin in a mouse model of RA showed reduced systemic and local inflammatory markers of arthritis, including reduced serum levels of IL-6, and a marked reduction in the number of Th17 cell, as well, as in the number and activation status of monocytes, macrophages, and neutrophils infiltrating arthritic joints [37]. The gene discussed is NAMPT; the disease is rheumatoid arthritis.