Similar to human CF airway fluids, levels of the CXCR2 ligands CXCL1 and CXCL2 (Figure 3(a)) and free DNA (Figure 3(b)) were highly increased in the BAL airway fluids of βENaC-Tg mice compared to wild-type controls. Here, CXCL1 is linked to cystic fibrosis.