As anti-SSB antibody seemed enhanced FITC-rSSB uptake by HL-60 (RA) cells (Fig 3C), we next investigated whether anti-SSB autoantibody or preformed SSB-anti-SSB ICs influenced IL-8 production from human PMNs and HL-60 (RA) cells. The gene discussed is CXCL8; the disease is rheumatoid arthritis.