IFNG and neoplasm: We found that PDT-induced apoptotic tumor cells are more capable of potentiating functional maturation of DCs (enhanced capability to secret IFN-γ and IL-12 and to induce T cell proliferation) than PDT-treated or freeze/thaw-treated necrotic tumor cells, particularly using a light dose of 0.5 J/cm2 with an ALA concentration of 0.5 mM (Figure 7).