Unlike lung CD4+ T cells, the production of IFN-γ by CD8+ T cells lasted through the chronic phase of infection (Fig 2B, d60), although the differences between unstimulated cells and p1-stimulated cells are not statistically significant the trend shows an increased percentage of IFN-γ+ CD8+ T cells in α-DEC-ESAT-treated mice. The gene discussed is CD8A; the disease is infection.