The t(6;14)(p21.1;q32.3) translocation that juxtaposes the CCND3 and IGH loci resulting in high-level expression of CCND3 has been reported in MM (Bergsagel and Kuehl, 2001) and in several subtypes of mature B-cell malignancies including DLBCL (Sonoki et al., 2001). This evidence concerns the gene CCND3 and diffuse large B-cell lymphoma.